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Daflon is indicated for the treatment of:
- Acute episodes of hemorrhoids
- Chronic hemorrhoidal conditions
Chronic venous insufficiency (both organic and functional) of the lower limbs, associated with symptoms such as leg heaviness, pain, and nighttime cramps
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✅ Description:
Daflon contains Diosmin and Hesperidin, which belong to the phlebotonic and vascular-protective class of drugs. These compounds enhance venous tone by prolonging the action of noradrenaline on the venous wall, thereby reducing venous capacitance, elasticity, and emptying time.
They also help maintain the integrity of the microcirculation by minimizing inflammation through inhibition of leukocyte activation and the subsequent release of inflammatory mediators such as prostaglandins and free radicals. This action improves capillary resistance and normalizes permeability.
Additionally, Daflon enhances lymphatic function by increasing lymphatic flow and oncotic pressure, improving lymph drainage.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Composition: Each film-coated tablet contains:
- Diosmin (micronised) BP 450 mg
- Hesperidin (micronised) INN 50 mg
Each DS (Double Strength) film-coated tablet contains:
- Diosmin (micronised) BP 900 mg
- Hesperidin (micronised) USP 100 mg
✔️ Dosage & Administration
Daflon 450 mg/50 mg
- Acute hemorrhoids: 3 tablets twice daily for 4 days, followed by 2 tablets twice daily for 3 days. Maintenance: 1 tablet twice daily as needed.
- Chronic hemorrhoids: 1 tablet twice daily.
- Chronic venous insufficiency: 1 tablet twice daily for 7 days. Duration may be extended based on clinical evaluation.
Daflon DS (900 mg/100 mg)
- Acute hemorrhoids: 1 tablet three times daily for 4 days, then 1 tablet twice daily for 3 days, followed by 1 tablet once daily for maintenance.
- Recurrent/chronic hemorrhoids: 1 tablet once daily for 3 months.
- Chronic venous insufficiency: 1 tablet once daily for 2–6 months.
- Venous leg ulcers: 1 tablet once daily for 2 months.
✔️ Side Effects
Occasional reports include mild gastrointestinal upset and autonomic symptoms such as discomfort. These events typically do not necessitate discontinuation.
✔️ Drug Interactions
No drug interactions have been reported during clinical use.
✔️ Contraindications
Individuals with known hypersensitivity should not use Daflon to any of its ingredients. Evaluation and management of chronic venous insufficiency should be done under medical supervision.
✔️ Use in Pregnancy and Lactation
Animal studies have not shown teratogenic effects. No harmful effects have been observed in humans to date. However, due to a lack of data on breast milk excretion, use during breastfeeding is not advised.
✔️ Precautions & Warnings
- Consult a physician if hemorrhoidal symptoms persist beyond 15 days.
- Limited data in cancer patients treated for lymphedema showed reduced edema without influencing cancer progression.
- Although long-term European clinical use has not shown carcinogenic or mutagenic risks, caution is advised in patients with a cancer history, as no dedicated studies are available in this group.
✔️ Storage Condition
Store below 30°C, protected from light and moisture. Keep out of children’s reach.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
